Combipres Sterile Eye Drops is comprised of two components: Brimonidine Tartrate & Timolol Maleate. Brimonidine Tartrate is a selective alpha-2 adrenergic receptor agonist having a dual mechanism of action. It decreases aqueous humor production and increases nonpressure dependent uveoscleral outflow. Timolol Maleate is a ß-adrenergic receptor antagonist that does not have significant intrinsic sympathomimetic, direct myocardial depressant, or local anesthetic (membrane-stabilizing) activity. It lowers IOP by reducing aqueous humor production. Therefore combination of both drugs gives a rapid onset of action, with peak ocular hypotensive effect seen within two hours of administration.
Agunstock Combipres Sterile Eye Drops: Each ml contains Brimonidine Tartrate INN 2 mg and Timolol Maleate BP equivalent to Timolol 5 mg.
Agunstock Combipres Sterile Eye Drops is indicated for the reduction of elevated intraocular pressure (IOP) in patients with glaucoma or ocular hypertension.