Each 1 mL of the solution contains 3 mg of ofloxacin, 10 mg of clotrimazole, 0.25 mg of beclometasone dipropionate, and 20 mg of lidocaine hydrochloride.
Audicare ear drops are a combination of ofloxacin (antibacterial), clotrimazole (antifungal), beclometasone (anti-inflammatory), and lidocaine (local anaesthetic). These ear drops are specially formulated to help maintain the natural environment of the external and middle ear.
Ofloxacin is a fluoroquinolone that exhibits antibacterial activity by inhibiting the bacterial DNA gyrase enzyme. Clotrimazole is a synthetic imidazole derivative that exerts fungicidal activity by inhibiting the biosynthesis of ergosterol, an essential component required for the synthesis of the fungal cell membrane, thereby preventing the growth of fungi.
Beclometasone dipropionate is a potent corticosteroid with anti-inflammatory activity. It inhibits the formation, release, and activity of prostaglandins, leukotrienes, and other inflammatory mediators.
Lidocaine hydrochloride is a locally applied anaesthetic that helps reduce ear pain and discomfort by inhibiting the transmission of pain signals.
Indications
Audicare Ear Drops are indicated for the treatment of superficial bacterial and fungal infections of the external auditory canal and middle ear caused by organisms susceptible to ofloxacin and clotrimazole.